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Primitive neuroectodermal tumor cell

One of a remarkable group of tumors that originate in cells from the primitive neural crest and share the same reciprocal translocation between chromosomes 11 and 22 and the same patterns of biochemical and oncogene expression. Some primitive neuroectodermal tumors (PNETs) occur in the brain while others (the peripheral PNETs) occur in sites outside the brain such as in the extremities, pelvis, and the chest wall.

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