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Title: 
Epigenetic profiling of WT and Ezh2-null MLL-AF9 murine leukemic cells
Measurement Type: 
Transcription Factor Binding (ChIP-Seq)
Factors: 
Genetic Characteristics
Summary: 
Leukemic cells from primary and secondary recipients of MLL-AF9-transduced WT and Ezh2-null cells were sorted for GFP and YFP expression and analyzed by Chip-Seq.
Curator(s): 
mmerrill

Group

Citations: 
Polycomb repressive complex 2 is required for MLL-AF9 leukemia.
Neff T, Sinha AU, Kluk MJ, Zhu N, Khattab MH, Stein L, Xie H, Orkin SH, Armstrong SA
Proc Natl Acad Sci U S A. 2012 Mar 27; 109(13):5028-33. PMID: 22396593. Abstract
Download: 
Study metadata (ISA-Tab: isa_16454_550999.zip)