New research from SBP reveals a novel gene regulatory system that may advance stem cell therapies and gene-targeting treatments for neurological diseases such as Alzheimer's disease, Parkinson's disease, and mental health disorders that affect cognitive abilities.
Scientists have narrowed in on a group of gut-residing immune cells that might predispose women to increased HIV infection risk and more severe disease.
The first complete genome assembly of planarian flatworm reveals a treasure trove on the function and evolution of genes.
Exposure to a compound used to treat migraines and seizures causes characteristics associated with autism, groundbreaking research with zebrafish has demonstrated.
Two different proteins work separately as well as synergistically to feed a small pool of stem cells that help bladder cancer resist chemotherapy, research led by a Johns Hopkins Kimmel Cancer Center scientist suggests. The finding, published online in Cancer Research, could lead to new targets to fight this deadly disease and potentially other cancers as well.
Scientists have derived and grown trophoblast stem cells for the first time, which will lead to better understanding of the human placenta.
Nerve cells in the skin help wounds to heal. When an injury occurs, cells known as glial cells change into repair cells and disseminate into the wound, where they help the skin to regenerate, researchers from the University of Zurich have shown.
People with higher levels of antibodies against the stem portion of the influenza virus hemagglutinin (HA) protein have less viral shedding when they get the flu, but don't have fewer or less severe signs of illness, according to a new study. This NIAID study is the first of its kind to evaluate pre-existing levels of these antibodies as a predictor of protection against influenza. The findings could have implications for flu vaccine development.
College-bound women are not less likely to enter specific fields because more math or science is required, but rather because of the gender discrimination they are likely to encounter in those fields, finds a new nationally representative longitudinal study published in the American Educational Research Journal.
The protein CD34 is predominantly regarded as a marker of blood-forming stem cells but it helps with migration to the bone marrow too.
A research team at GW School of Medicine and Health Sciences found that latent HIV reservoirs exhibit resistance to elimination by CD8+ T-cells.
Researchers at The Scripps Research Institute recently published a study in the journal Cell Death and Differentiation identifying factors crucial to mesenchymal stem cell differentiation, providing insight into how these cells should be studied for clinical purposes.
A University of Queensland discovery has deepened our understanding of the genetic mutations that arise in different tissues, and how these are inherited. Researchers from UQ's Queensland Brain Institute, led by Dr. Steven Zuryn, found the rates of genetic mutations in mitochondrial DNA vary across differing tissue types, with the highest rate occurring in reproductive cells.
A new synthetic hormone promises to tease apart the many different roles of the plant hormone auxin and could lead to a new way to ripen fruit.
Researchers at EPFL have created artificial molecules that can help the immune system to recognize and attack cancer tumors. The study is published in Nature Methods.
A study led by UNC Lineberger Comprehensive Cancer Center researchers and published in the Journal of Cell Biology examined the role of the physical structure of the nucleus in cell movement through different surfaces.
Researchers from Charité - Universitätsmedizin Berlin have discovered that the survival of cancer stem cells is dependent on the 'Hedgehog signaling pathway'. Targeting this pathway had previously shown no effect on the growth of colorectal cancer. Now, Charité scientists have demonstrated that using different drugs to target a specific aspect of the pathway may yield better treatment outcomes for patients. Results from this research have been published in the journal Cell Reports*.
KAIST medical scientists identified a cellular mechanism causing inflammatory changes in regulatory T cells that can lead to severe viral hepatitis. Research on this mechanism will help further understand the nature of various inflammatory diseases and lead to the development of relevant clinical treatments.
In a scientific first, researchers at the Gladstone Institutes turned skin cells from mice into stem cells by activating a specific gene in the cells using CRISPR technology. The innovative approach offers a potentially simpler technique to produce the valuable cell type and provides important insights into the cellular reprogramming process.
Scientists have solved a longstanding puzzle of how cells are able to tightly package lengthy strands of DNA when they divide -- an essential process for growth, repair and maintenance in living organisms.
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